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Coupling of oceanographic state to the dark proteome: a foundation for genome-informed marine productivity modeling

Phytoplankton drive ~46% of global primary production, yet whether their protein repertoires encode ocean conditions - and whether reference databases capture the environmentally responsive fraction - is unknown. We used a protein language model to classify 447.7 million proteins from 2,357 samples and analyzed domain profiles for 231.7 million algal proteins across 2,044 samples. Under spatial…

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David N. Spergel

Director: Center for Computational Astrophysics, FlatironCharles Young Professor Emeritus, Princeton UniversityCo-Chair: NASA WFIRST Form.

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