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Where to watch 49ers vs. Cardinals today: Time, TV channel for Week 3

It's an NFC West showdown at Levi's Stadium between the San Francisco 49ers and Arizona Cardinals. Here's where to watch it.

The San Francisco 49ers will host the Arizona Cardinals on Sunday, September 26, 2026, in what is expected to be one of the most challenging games of the season for the 49ers. The Cardinals defeated the Los Angeles Chargers 26-14 in Week 1, while the 49ers lost 31-7 to the Seattle Seahawks.

Defensive end Nick Bosa will not play in this matchup due to injuries, leaving the 49ers' defensive line depleted. This could present a significant challenge for the 49ers' defense, which has been fortunate to play with large leads throughout the season. This may be the first time the group faces a tight game all the way through the fourth quarter.

To watch the game, it will be broadcast on Fox, with a livestream available on Fubo (which offers a free trial). The game will start at 1:05 pm Pacific Time. Tickets for the 49ers can be purchased now.

Expert predictions suggest that the 49ers will emerge victorious, with a spread of -7.5 and an over/under of 48.5 points. The moneyline odds have the 49ers at -400 and the Cardinals at +310.

Written by urgent.news from Yahoo Sports's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

Read the original at sports.yahoo.com →

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