NFL Week 3 expert picks, predictions: Moneylines, against the spread

Week 3 of the 2026 NFL season is well underway, and it has proven to be an unpredictable start to the year. Only eight teams have remained undefeated after two games, including an unlikely contender: the Las Vegas Raiders. Meanwhile, several teams are currently 0-2, including the Houston Texans, Indianapolis Colts, Tampa Bay Buccaneers, and Los Angeles Chargers. The Green Bay Packers are only one loss away from joining the 0-3 club.

Given the uncertainty surrounding the early standings, predicting outcomes for Week 3 becomes a challenging task. For instance, can the Buccaneers avoid an 0-3 start against a resurgent Minnesota Vikings squad with Kyler Murray back in the lineup? How will the Raiders fare against a rising New Orleans Saints team? Additionally, the Monday night game between the Eagles and Bears will be a crucial matchup to determine if either team has legitimate NFC contender status.

As usual, our team provided predictions for every game on this week's schedule. Our selections focused solely on the straight-up winners, but a few of us also ventured into against the spread and over/under game total territory. You can view all of our picks for this week, including those for the Detroit Lions vs. New York Jets matchup, by clicking here.