Thousands of women in Spain forced to hunt for medicine just to feel human, what to do if you are affected

Spain is grappling with a shortage of hormone replacement therapy (HRT) treatments since March 2026, leaving thousands of women struggling to maintain their quality of life. Around 400,000 women in Spain rely on these therapies, and demand has steadily increased in recent years. Lenzetto, an oestrogen spray applied to the skin, was at the heart of the issue, with a fault in its dispenser causing the shortages.

Spain's medicines regulator, the AEMPS, declared the shortage on March 16 and expects supply to return to normal by November. However, substitutes like gels and patches have become harder to find, causing a ripple effect in the market. Bijuva, a combined oestrogen-progesterone treatment, is also unavailable due to its manufacturer pausing production.

Gynaecologist Mercedes Herrero stresses the importance of clear information for patients, explaining that sprays can usually be swapped for patches or creams, and oral oestrogen tablets are an option for those who can take medication that way. However, interruptions often lead patients to stop taking their treatment altogether. One woman, Silvia, was prescribed Lenzetto but is now waiting until November to try supplements recommended by her doctor.

Julia found a solution through Farmahelp, a platform that helps locate medicines affected by shortages, but she opted for a different therapy due to the uncertainty. Rebeca Martin launched a Change.org petition with over 20,000 signatures, calling for authorities to act before shortages happen and to guarantee accessible alternatives.

The advice for those affected is to contact their GP or gynaecologist before a prescription runs out and to check with multiple pharmacies for availability. Keeping an eye on official updates from the AEMPS can also provide a clearer picture of when the shortage is likely to ease.