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Mitochondrial protein complexes: A single amino acid can jeopardize their stability

Removing a single amino acid can determine whether new proteins assemble into stable complexes within mitochondria. An enzyme carries out this precise trimming at the start of mitochondrial proteins. Without it, numerous protein complexes lose their stability, according to a study led by Dr. Nora Vögtle of Heidelberg University and Dr. Pitter Huesgen of the University of Freiburg. In their work…

phys.org ·59m ago

Mitochondrial protein complexes: A single amino acid can jeopardize their stability

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