Anthropic’s Claude finds new CRISPR-like system in viruses
Anthropic says its Claude AI has discovered ART, a previously uncharacterised enzyme system in bacteriophages with a CRISPR-like repeat array. Around 950 Claude agents searched DNA data for 21 hours to find it. CEO Dario Amodei says its function and significance aren't clear yet, but calls it work he would have been proud to do as a PhD student. CRISPR pioneer Feng Zhang says it merits further…
Anthropic's AI, Claude, has discovered a previously unknown enzyme system in viruses that infect bacteria, which shares a similar structure to CRISPR, the famous gene editing tool. Named array-associated reverse transcriptase (ART), the system is composed of three parts: a reverse transcriptase enzyme that copies RNA to DNA, an unknown-function gene, and a long array of DNA repeats.
This repeat array is what leads to the CRISPR comparison, as it stores RNA sequences, making the system programmable like CRISPR. While the precise function and biotech usefulness of ART are still unclear, it marks the first result from Anthropic's new life sciences research group and wet lab, established in the Bay Area this spring.
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