Persistence of mucosal CAR-T cells and inflammatory remodeling in enterocolitis associated with BCMA CAR-T cell therapy
Nature Medicine, Published online: 23 September 2026; doi:10.1038/s41591-026-04632-y A multimodal analysis of patients with multiple myeloma who developed enterocolitis following BCMA CAR-T cell treatment shows that CAR-T cell-associated enterocolitis is not defined exclusively by plasma cell and B cell depletion, but is associated with expansion of cytotoxic CAR-T cells and coordinated…
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