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Dynamic social envirotypes demonstrate adolescent brain dysconnectivity is contextual

The adolescent social environment and dynamics therein have been linked to divergent brain organization and greater risk of psychopathology later in life, suggesting the neural underpinnings of mental health may depend on social context. To examine this, we leveraged longitudinal ABCD Study data to identify dynamic social envirotypes, or distinct trajectories of social environment change over…

Adolescent brain functionality varies based on the social environment, potentially influencing mental health outcomes later in life, according to a study of the adolescent social environment. Researchers analyzed longitudinal data from the ABCD Study, identifying distinct patterns of social environment change over four years known as dynamic social envirotypes.

These envirotypes differed in terms of mental health outcomes, changes in mental health, and overall brain connectivity. Each dynamic social envirotype displayed a unique pattern of brain network organization. Importantly, the links between functional connectivity and internalizing or externalizing problems varied across dynamic social envirotypes.

The highest and lowest social resource envirotypes showed opposing associations between connectivity and symptom severity. These findings suggest that brain connectivity patterns associated with mental health are not universal but rather context-dependent. The study challenges conventional wisdom about the neural basis of psychopathology, highlighting the importance of context in understanding and addressing mental health issues during adolescence.

Written by urgent.news from bioRxiv's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

Read the original at biorxiv.org →

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