Chicago Cubs vs. Miami Marlins preview, Wednesday 9/23, 6:40 CT

The Chicago Cubs will face the Miami Marlins in a game on Wednesday, September 23, 2026, at 6:40 CT at Wrigley Field. The Cubs have performed well on Wednesdays this season, tying with their best records on Saturdays. They are 15-10 on Wednesdays, behind Monday's 11-7 record. The team is 7-5 at home on Wednesdays, trailing Thursday's 5-1 mark, Monday's 9-2 performance, and Saturday's 8-5 total.

The Cubs have a strong track record of overcoming deficits, with a 41-22 record when they come from behind. However, their latest loss, after tying the score at 2, marked their third consecutive defeat, sixth of seven and eighth of ten games since August 21. Before this downturn, they had won 22 of 24 games in similar situations.

With runners in scoring position, the Cubs struggled last night, hitting only 1 for 18. They had similar difficulties in previous games, including a walk-off loss in Seattle on August 21 and a 4-3 home defeat against the Pirates on April 11. The Cubs have faced challenges with runners in scoring position in several games, including 10 at bats with one hit in a 6-0 loss at Texas on May 9, and no hits in 13 at bats in other games.

Looking back into Cubs history, Carlos Zambrano threw seven strong innings in 2006, hitting his sixth home run of the season and tying the franchise record. This memorable game, played on September 23, saw the Cubs defeat the Reds 11-4. The lineup and weather forecast for the game are provided, along with links to follow the action live on Marquee Sports Network and MLB.com.

The Marlins' lineup and the key pitcher, Kevin Gausman, are also discussed. Gausman's recent performances are analyzed, with a focus on his potential effectiveness against the Marlins. The Marlins' pitcher, Ryan Gusto, has had a mixed record against strong teams recently, but Gausman's ability to hold opposing teams to one run in a recent game could bode well for the Cubs' chances. The Marlins' game preview and streaming options are also listed for those interested in following the action closely.