Review of Prepregnancy Care and Counseling
To the Editor In reading the otherwise comprehensive article by Dr Cooper and colleagues on prepregnancy care and counseling, we were surprised by the lack of discussion about testing for iron deficiency. Iron deficiency, the world’s most common micronutrient deficiency, is epidemic in young women. Studies of healthy reproductive-aged female patients report that iron deficiency is present in…
The article by Dr. Cooper and colleagues on prenatal care and counseling omitted the vital topic of iron deficiency screening. Iron deficiency, the most widespread micronutrient deficiency, plagues a significant portion of young women, with studies indicating a prevalence of around 38% when using a ferritin threshold of 30 μg/L. Despite this, discussions surrounding the most common cause, heavy menstrual bleeding, are often absent, leading to symptoms being overlooked and normalized.
Iron deficiency's prevalence varies during pregnancy, with studies showing a range from 21% to 84% at different gestational stages, with the strongest predictor of severe deficiency in the third trimester being a ferritin level of less than 60 μg/L at 15 weeks. Research also suggests a link between maternal iron deficiency and adverse outcomes in offspring, such as language and motor skill impairments at 2 years of age.
The consequences of iron deficiency, whether anemic or not, extend to symptoms like fatigue, restless legs syndrome, pica, and cognitive fog. Economic analyses suggest that screening for iron deficiency and treating it when detected are cost-effective in reproductive-aged women. Consequently, several professional organizations, including the International Federation of Gynecology and Obstetrics, the European Hematology Association, and others, now endorse screening for iron deficiency before pregnancy, as it's highly prevalent and can have significant health implications for both mothers and their future children.
Therefore, the article aligns with the growing trend of recommending iron deficiency screening for all reproductive-aged and pregnant women, regardless of anemia.
Written by urgent.news from JAMA's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.
Also reported by 1 other outlet
- Review of Prepregnancy Care and Counseling jamanetwork.com
