Electrophysiological dependent antiarrhythmic drug response in population-based models of paroxysmal atrial fibrillation
Response to antiarrhythmic drugs varies markedly across patients with atrial fibrillation (AF), suggesting that treatment efficacy depends on the interaction between drug-specific mechanisms and patient-specific electrophysiological substrate. Here, we used population-based computational models to investigate how electrophysiological substrate and inter-individual ionic variability influence…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
