Complete genome sequence of Comamonas testosteroni TA441 and comparative analysis of steroid degradation gene clusters across Proteobacteria and Actinomycetota

Comamonas testosteroni TA441 is a model aerobic steroid-degrading bacterium whose sterane degradation pathway has been elucidated in greater detail than that of any other bacterium to date. Similar pathways have been identified in many bacterial genera, including members of Proteobacteria and Actinomycetota, such as Mycobacterium tuberculosis. Steroid degradation genes in TA441 form an…

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