ARCHER-LD: Rapid Long-Range Linkage Disequilibrium Calculations at Biobank Scale using GPU Acceleration
Linkage disequilibrium (LD) information from one's own dataset is considered optimal for downstream analyses such as statistical fine-mapping. However, the computational complexity ({approx}N2 / 2 computations for N variants) lead most studies to use external reference panels, such as from 1000 Genomes. To capture LD across all variant pairs in biobank-scale whole-genome sequencing (WGS) datasets…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
