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An Open-Source 3D-Printed Vacuum Manifold for Automated DNA Isolation in the Opentrons Flex and OT-2

Laboratory automation is increasingly being adopted in academic research to improve throughput, reproducibility, and integration with computational workflows. A common bottleneck in molecular biology workflows is the isolation of DNA, typically performed with spin-column kits relying on centrifugation or vacuum. Existing automation solutions depend on magnetic separation systems requiring costly…

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