He Won the Nobel Prize for Protein Design. Now He Uses AI to Create Molecules Not Found in Nature

David Baker, who recently won the Nobel Prize in Chemistry for his work in computational protein design, is using AI to create molecules not found in nature. The initiative, led by the Allen Institute, University of Washington, and the Fred Hutchinson Cancer Center, aims to develop databases, models, and tools for future medicines and technologies.

These could include new cancer treatments, enzymes to break down ocean plastics, and biological computers. By leveraging AI, scientists can explore possibilities never observed in nature, similar to historical transformations like industrialization, electrification, and the digital revolution. However, venturing into uncharted biological territory raises questions and risks.

While computational design allows for evaluation of these risks before synthesis, potential issues include unintended interactions with living systems, unexpected environmental effects, or misuse. Despite the potential, it's crucial to understand and mitigate these risks before deploying new biological technologies.