A mechanistic digital twin model for epigenetic therapy optimization in triple-negative breast cancer
Epigenetic therapies offer a promising approach to cancer treatment by modulating chromatin states that govern tumor cell identity, plasticity and therapeutic response. However, predicting and optimizing the effects of such interventions remains challenging. Here, we developed a digital twin framework that integrates mechanistic models of chromatin regulation, in vitro cell-state and treatment…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
