IonOpticks releases Aurora Series 5 liquid chromatography technology
Scientific instrument maker IonOpticks launched its Aurora Series 5 liquid chromatography columns featuring integrated CoreJet emitter technology to improve operational stability and lower unit costs in proteomics research
Melbourne, Australia - IonOpticks, a global leader in high-performance chromatography solutions for LC-MS-based proteomics, has unveiled the Aurora Series 5. This release marks the most significant robustness upgrade in the platform's history. Extensive testing on a Thermo Scientific Vanquish Neo UHPLC coupled to an Orbitrap Astral Zoom mass spectrometer demonstrated that Series 5 can sustain over 10,000 unique protein identifications across more than 1,000 injections during an 8-minute, 120-samples-per-day method, with no increase in backpressure beyond 1,400 runs.
This upgrade enables nanoflow-level depth and sensitivity, transforming the Aurora Series into a routine, high-throughput workflow rather than a reserve for landmark experiments.
The core of the upgrade lies in two platform-wide technological advancements: the CoreJet integrated emitter technology and a redesigned nanoZero union. These innovations deliver consistent backpressure, enhanced spray stability, and increased reliability over prolonged use without sacrificing the performance that has established Aurora Series as a benchmark for deep and sensitive proteomics.
Xavier Perronnet, IonOpticks' Chief Executive Officer, stated that Series 5 combines exceptional performance with a new level of robustness, enabling laboratories to confidently use the columns routinely across demanding workflows. The company's Chief Product Officer, Dr. Jarrod Sandow, emphasized that true robustness involves maintaining performance despite the variable and demanding conditions of everyday laboratory use.
Aurora Series 5's enhanced architecture eliminates concealed unions between the column and emitter, reducing dead volumes, improving resistance to early clogging and overpressure events, and extending column longevity. The redesigned nanoZero union ensures consistent voltage to the liquid passing through the column, supporting improved spray stability and simpler column setup.
The coefficients of variation remain below one percent for median protein and peptide identifications, indicating consistent performance across a column's service life and between columns.
In addition to its robustness, Series 5 gains additional protection from sample-derived contamination when paired with an IonOpticks NanoShield® C18 trap column, further extending column life and providing a compelling value proposition for laboratories processing hundreds or thousands of samples. Aurora Series 5 upholds the high-performance nanoflow chromatography standards set by IonOpticks, offering depth and sensitivity while being designed to withstand the demands of everyday proteomics.
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