Urgent.News

What's breaking now, across thousands of outlets.

Health & Medicine

An integrated genome-wide resource reveals distinct replication environments of DNA breakage in human cancer cell lines

Replication stress is a major source of genome instability in cancer, yet the genomic features that determine where DNA double-strand breaks (DSBs) arise remain incompletely defined. Here, we establish an integrated genome-wide resource of DSBs, DNA replication, replication timing, transcription, and R-loops in two widely used cancer cell lines, U2-OS and HeLa, under steady-state conditions and…

We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.

Read the original at biorxiv.org →

More in Health & Medicine

DIPHTHERIA CRISIS: THE IMMUNISATION GAP

PAT ONUKWULI argues for surveillance and a catch-up vaccination in schools and communities An earlier article, “Nigeria’s Immunisation Gap,” warned that vaccine availability must not be mistaken for…

More from Tuesday 15 September →