Conserved microglial programmes, non-transferable classifiers: boundaries of the single-cell TBI molecular clock
Background: Traumatic brain injury (TBI) pathology evolves over hours to months, and molecular staging could complement clinical and imaging-based assessment. Single-cell transcriptomics captures cell-type-resolved temporal programs, but whether a transcriptional "molecular clock" trained on one injury model can be transferred to others remains unknown. Methods: We compiled four public mouse TBI…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
