One mechanism, two diseases: Involvement of enzyme–substrate complexes in the pathogenesis of celiac disease and rheumatoid arthritis
Proceedings of the National Academy of Sciences, Volume 123, Issue 37, September 2026. Celiac disease (CeD) and rheumatoid arthritis (RA) share several key features. In both diseases HLA class II allotypes are the major genetic determinants, in both diseases there are antibodies to posttranslationally modified peptides (i.e., deamidated ...
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