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When is Louisville vs Ole Miss? Time, TV, prediction for Week 1 game

What time will Louisville football's 2026 season opener against Ole Miss begin Sunday? Kickoff time, TV channel, predictions for the game.

Louisville and Ole Miss face off in a highly anticipated college football matchup on Sunday night at Nissan Stadium in Nashville. This game marks the first Associated Press Top 25 clash of the season, with Louisville entering the match as the No. 24 ranked team and Ole Miss at the No. 9 spot. The Cards have struggled against ranked opponents, posting a 10-16 record in such contests, including a recent loss to Notre Dame in September 2024.

However, the Rebels have a 0-1 record against Louisville, with the Cardinals prevailing 43-24 in the 2021 season opener. Louisville will aim to right the ship and end Trinidad Chambliss' early Heisman buzz with an upset win over Ole Miss. The game will be televised on ABC and can be attended as a neutral-site contest in Nashville.

Tickets for the match can be purchased through StubHub. Season opener predictions suggest a tightly contested game, with Louisville favored at 31, Ole Miss at 28. Set to kick off at 7:30 p.m., the matchup promises a mix of excitement and uncertainty for both teams as they begin their respective 2026 seasons.

Written by urgent.news from Yahoo Sports's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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