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Runner's high study finds cannabis-like signaling molecules rise over extreme distances

A marathon, 100 kilometers (62 miles) or even 230 kilometers (143 miles) in a single effort: Anyone running such distances puts enormous strain on their body. At the same time, levels of the body's own cannabis-like signaling molecules rise significantly. Dr. Michael Siebers from the Institute of Forensic Psychiatry and Sex Research at the University of Duisburg-Essen and his team have, for the…

Runner's high study finds cannabis-like signaling molecules rise over extreme distances

A new study has revealed that endocannabinoids, akin to cannabis molecules, increase throughout an entire marathon and even after extreme ultramarathon distances. Researchers from the University of Duisburg-Essen tracked these molecules in 19 experienced runners over a 25-mile course and compared the results with 36 participants who ran longer distances.

Blood samples were taken before and after the runs, showing a clear rise in anandamide, a key endocannabinoid, over time. While this indicates the endocannabinoid system remains active during extended runs, the exact role it plays in the runner's high, characterized by reduced anxiety and euphoria, remains unclear.

Written by urgent.news from Medical Xpress's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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