USC vs Fresno State Prediction: Will the Trojan Defense Be Better?
USC was fine in the opener, but the defense left something to be desired. Will it be better against Fresno State? Here's the CFN preview and prediction.
In the upcoming matchup between USC and Fresno State on September 4, 2026, at 9:00 PM ET, the Trojans' defense may face challenges as Fresno State aims to run the ball effectively. Fresno State, a newcomer to the Pac-12, defeated USC 24-7 in their last meeting, the 1992 Freedom Bowl. However, since then, USC has won the last five contests.
Fresno State's quarterback, Luke Weaver, led the team to an 8-0 record when they ran at least 32 times last season. Meanwhile, USC's offense was razor-sharp early, leading 35-3 against San Jose State. Their defense faltered in the final quarter, giving up 23 points. Jayden Maiava, a key player for USC, had 25 completions on 29 attempts for 286 yards and two touchdowns, along with a rushing touchdown.
Despite Fresno State having excellent defensive talent, their loss of key cornerbacks and the Trojans' potent offense make USC the favored team with a consensus line of USC -23.5, over/under of 51.5 points.
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