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Common supplements rival antibiotics for severe gum disease

Omega-3 and low-dose aspirin matched the effectiveness of antibiotics in a year-long study of patients with severe gum disease, with both approaches helping about 58% reach the treatment goal. The unexpected result could point to a new way to treat some patients while reducing reliance on antibiotics and the growing problem of antibiotic resistance.

A study by Brazilian researchers from several universities and Harvard University has shown that a combination of omega-3 fatty acids and low-dose aspirin may be as effective as antibiotics in treating severe gum disease. The research, published in the Journal of Periodontology, involved 109 patients with advanced periodontitis who were followed for one year.

Periodontitis is a chronic inflammatory disease that can damage the bone and teeth that support the teeth. In advanced cases, it can lead to tooth loss. The participants were divided into four groups, each receiving different treatment regimens. Two groups received antibiotics, while the other two received either omega-3 or aspirin.

A third group received both omega-3 and aspirin for six months. After one year, about 58% of patients treated with antibiotics had achieved the clinical target of having no more than four remaining deep periodontal pockets. The group receiving omega-3 and aspirin also achieved a nearly identical result, with 57.7% of participants meeting the target.

The combination of antibiotics and omega-3 or aspirin did not produce any additional benefit over either strategy alone. The study's findings suggest that omega-3 and low-dose aspirin could be a viable alternative to antibiotics for treating severe gum disease, particularly in patients at risk of antibiotic resistance. However, the researchers caution that further studies are needed to confirm these results and to better understand the underlying mechanisms.

Written by urgent.news from ScienceDaily's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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