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A liver signaling pathway may explain why colorectal cancer weakens muscle and bone

Researchers at the University of Colorado Anschutz and Indiana University School of Medicine have identified a biological process that may help explain why colorectal cancer can cause severe muscle and bone loss, especially in its most advanced stages. The condition, known as cancer cachexia, can leave patients weak, make everyday activities more difficult and make it harder to tolerate cancer…

A liver signaling pathway may explain why colorectal cancer weakens muscle and bone

We haven't written up this one. Medical Xpress has the full story — the link below goes straight to it.

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Samsung Bioepis Initiates Phase 1 Clinical Trial for SB35, A Biosimilar Candidate Referencing Taltz (Ixekizumab)

Samsung Bioepis Co., Ltd. announced on Aug. 28 the initiation of Phase 1 clinical trial for SB35, a biosimilar candidate referencing Taltz (ixekizumab).The Phase 1 clinical trial for SB35 is a…

  • Samsung Bioepis begins Phase 1 trial for SB35 biosimilar on August 28
  • Study compares pharmacokinetics, safety, tolerability, immunogenicity of SB35 vs Taltz
  • Primary outcomes measured: AUCinf, Cmax, AUClast from Day 1 to Day 85

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