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Does the shingles vaccine cut heart disease risk? Mounting evidence suggests a link

Nature, Published online: 26 August 2026; doi:10.1038/d41586-026-02663-6 Large study finds that people who received the ‘recombinant’ vaccine for the viral condition had a lower risk of cardiovascular problems.

A shingles vaccine, which is given to prevent the pain and blisters of shingles in older adults, may also be linked to a lower risk of dementia, according to a recent study. Researchers found that individuals who received the vaccine had a 20% lower relative risk of developing dementia over the next three years compared to those who did not get vaccinated.

This finding is based on a "natural experiment" created by a birthday cut-off for vaccine eligibility in Wales, which allowed researchers to compare two similar groups - those who were eligible for the vaccine and those who were not. The study also found that the vaccine's protective effect was seen only in women, not men. However, subsequent studies in Australia, Canada, and the U.S. have replicated these results and found a protective effect of the shingles vaccine against dementia for both sexes.

While there is still some skepticism from certain epidemiologists, the scientific consensus is growing that the shingles vaccine may have an unexpected benefit in reducing the risk of dementia.

Written by urgent.news from Your Local Epidemiologist's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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