Dementia Drug Helpful With Lupus Brain Fog
(MedPage Today) -- Cognitive dysfunction in people with systemic lupus erythematosus (SLE) -- aka "lupus brain fog" -- was significantly relieved with the Alzheimer's dementia drug memantine in a small placebo-controlled trial. Twelve weeks...
A small trial has shown that the Alzheimer's drug memantine may help alleviate cognitive dysfunction, or "lupus brain fog," in people with systemic lupus erythematosus (SLE). Over 12 weeks, memantine treatment led to a significant improvement in performance on the RBANS test compared to placebo. The study, called ClearMEMory, enrolled 56 adults with NPSLE and found that memantine was well-tolerated, with most patients completing the trial.
However, the sample size was small, and the trial duration was short, limiting the study's conclusions.
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