49ers injury updates: Latest on George Kittle, Mike Evans, Nick Bosa

The San Francisco 49ers continued their preseason practice on Tuesday, still dealing with a variety of injuries among their roster. Head coach Kyle Shanahan provided updates on several key players as the team prepared for their first regular season game against the Los Angeles Rams on September 10.

Veteran tight end George Kittle received good news as he was activated from the physically unable to perform (PUP) list after recovering from a torn Achilles suffered in a previous game. Kittle is working on non-competitive drills, with the possibility of playing in their Week 1 matchup against the Rams.

Wide receiver Mike Evans, another addition to the team this offseason, continues to battle tightness in his groin. He did not participate in Tuesday's practice but has been throwing and catching with teammates. Shanahan expressed hope that Evans could return to action next week.

Pro Bowler Nick Bosa, who suffered an ACL injury during the 2025 season, is making progress and is expected to start practicing soon. Shanahan said Bosa is "doing good" and hopes he can join the team in practice within the next three days.

Running back Christian Kirk, who signed a one-year deal with the 49ers, has been limited due to a calf injury. Shanahan stated that it is "possible" Kirk may be placed on injured reserve, though it is still uncertain at this point.

Injury updates also included Christian McCaffrey, who was present and active during the practice, appearing to be fully recovered. Meanwhile, rookie edge rusher Romello Height has an ankle injury, and defensive lineman Mykel Williams and running back Isaac Guerendo remain on the PUP list.