Loss of epitranscriptomic mitochondrial RNA surveillance drives epithelial type I interferon and inflammation in autoimmunity
Proceedings of the National Academy of Sciences, Volume 123, Issue 35, September 2026. SignificanceEpithelial cells are central gatekeepers of immune homeostasis, yet how they lose control and initiate chronic interferon activity and inflammation in autoimmunity has remained a mystery. We uncover a critical epitranscriptomic checkpoint that ...
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