Researchers find no symptom worsening following mindfulness-based cognitive therapy
Madison's Center for Healthy Minds (CHM), along with the UW–Madison Department of Educational Psychology and a multi-university team, has found no evidence that mindfulness-based cognitive therapy (MBCT) increases the risk of symptom worsening in a meta-analysis published in JAMA Network Open.
Researchers have found no evidence that mindfulness-based cognitive therapy (MBCT) increases the risk of symptom worsening in people with recurrent depression, according to a new meta-analysis published in JAMA Network Open. The study, led by the Madison's Center for Healthy Minds and the UW–Madison Department of Educational Psychology, combined data from nine randomized controlled trials involving 1,258 adult patients with recurrent depression in remission.
The analysis compared the odds of increased depressive symptoms after MBCT treatment to control conditions, and found no increased risk of symptom worsening with MBCT. Interestingly, some secondary analyses indicated that MBCT may even decrease the risk of symptom worsening compared to other treatments, such as antidepressants. The study's authors, including Simon Goldberg, emphasize that the results support the continued use of MBCT as an evidence-based treatment for recurrent depression, but note that the trials focused on individuals in partial or full remission from depression, so the findings may not apply to those with acute depression or other clinical populations.
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