UPLC-ESI-MS based lipidomics revealed novel biomarkers in insulin receptor knockdown induced type 2 diabetes model of Drosophila
Type 2 diabetes (T2D) is a prevalent metabolic disorder affecting millions worldwide, characterized by insulin resistance and impaired glucose homeostasis. While mammalian models are widely used, Drosophila melanogaster provides a powerful alternative due to its conserved insulin signaling pathways, genetic tractability, and suitability for high throughput studies. In addition to glucose…
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