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Hodgkin lymphoma survivors face twice the risk of death compared to average American adult

Adults who have survived Hodgkin lymphoma (HL) for at least five years face significantly elevated long-term health risks, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

Hodgkin lymphoma survivors face twice the risk of death compared to average American adult

A new study finds that adult survivors of Hodgkin lymphoma (HL) who have been cancer-free for at least five years face twice the risk of death compared to the average American adult. Led by researchers at The University of Texas MD Anderson Cancer Center, the retrospective analysis of data from 2000 to 2017 examined over 20,000 survivors, with an average age of 36.

The researchers observed 2,899 deaths among these patients, while only 1,481 deaths would have been expected in the general population. While many of these deaths were due to cancer, noncancer conditions also became more prevalent in this group. The study's lead author, Dr. Luis Malpica Castillo, emphasizes the importance of survivorship care focused on cardiovascular health, secondary cancers, and chronic conditions to improve long-term survival outcomes.

The elevated risk of death was also present in those who survived at least 10 years, with noncancer causes accounting for the majority of excess mortality. Younger adults diagnosed between ages 20 and 39, as well as several racial and ethnic minority groups, experienced the highest relative risks. However, mortality rates have decreased among patients diagnosed in more recent years, reflecting ongoing advancements in treatment.

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