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Spliceosomal miR-99b Regulates SPACA6-AS1 Pre-mRNA Levels and Promotes Malignant Phenotypes in Breast Cancer

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression primarily in the cytoplasm. However, emerging evidence highlights their additional roles in the nucleus. In particular, spliceosomal miRNAs have been implicated in novel regulatory functions, including the modulation of gene expression. Here, we investigate the nuclear role of spliceosomal miR-99b in breast cancer cells,…

We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.

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Building-level wastewater surveillance of antimicrobial resistance in the general, student and hospital-associated populations

Scientific Reports, Published online: 20 August 2026; doi:10.1038/s41598-026-67590-y Building-level wastewater surveillance of antimicrobial resistance in the general, student and hospital-associated…

  • Wastewater surveillance tracks AMR in Perugia's general, student, and hospital populations
  • Third-generation cephalosporin resistant E. coli prevalence consistent across populations
  • Vancomycin-resistant enterococci levels highest in hospital wastewater

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