Supercentenarians have a cellular superpower
Could this secret cellular weapon be the key to longevity?
People who live far beyond the age of 100 possess a unique cellular advantage, according to recent research. These individuals have a higher concentration of a special type of immune cell known as CD4 cytotoxic T lymphocytes, or CD4 CTLs. CD4 CTLs play a crucial role in the body's immune response by targeting and destroying harmful cells, including viruses, inflammation, and even cancer.
In exceptional cases, these cells seem to proliferate and specialize as people age, which could explain their extended life span. The findings, based on a study of 28 individuals spanning various age groups, suggest that this increase in CD4 CTLs is not merely a consequence of aging but may be an adaptive response to persistent antigens in the body.
Researchers from the University of Osaka in Japan are optimistic that further studies could uncover the specific targets of these cells and their role in younger individuals, some of whom also exhibit high levels of CD4 CTLs. The discovery of these cells' potential to adapt and combat harm in later life is a significant step forward in understanding the mechanisms behind longevity.
Written by urgent.news from Scientific American's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.
