Newly found 'immune organ' inside skull directs brain defense
Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders against brain cancer before distant lymph nodes get the signal that abnormal cells are present. The researchers also found evidence of similar immune cells in human skull bone…
Researchers at Washington University School of Medicine have discovered immune-like structures in the skull bone marrow of mice for the first time, which appear to function as rapid first responders against brain cancer, even before distant lymph nodes receive the signal. The study, published in Nature, suggests the brain communicates with the immune system and has positioned immune "security stations" closer than other organs.
The skull bone marrow harbors previously unrecognized hubs for brain-specific immune responses, potentially transforming how we understand neuroimmune interactions and treating neurological diseases.
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