Moderna and Merck say their personalized mRNA melanoma vaccine significantly reduced both cancer recurrence and spread in a late-stage trial. The treatment could reach patients as soon as next year if regulators approve it. Reuters reports: Moderna developed the vaccine with Merck and tested it together with immunotherapy drug Keytruda, a widely used treatment for melanoma. [...] This is the…
Moderna and Merck have announced that their personalized mRNA melanoma vaccine significantly reduced both cancer recurrence and spread in a late-stage trial. The treatment, which combines Merck's Keytruda with a made-to-order mRNA vaccine from Moderna, could reach patients as soon as next year if regulators approve it. This is the first positive late-stage trial result for an mRNA cancer vaccine, which trains a patient's immune system to fight tumors by targeting specific mutations in those cells.
The trial enrolled 1,137 high-risk patients with stage IIB-IV melanoma, and the companies reported no new safety signals in the study.
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