Vitamin deficiency could lead to mild cognitive impairment, finds NIN study
Mild cognitive impairment (MCI) is a condition in which a person experiences changes in memory or thinking abilities, but can still largely carry out daily activities independently. It is considered an intermediate stage between normal ageing and dementia.
A study conducted by the National Institute of Nutrition in Hyderabad has revealed a significant connection between low levels of essential vitamins and mild cognitive impairment (MCI) in older adults. MCI is a condition characterized by memory or thinking changes, yet individuals can typically manage daily activities on their own, marking an intermediate stage between normal aging and dementia.
The researchers examined 184 adults aged between 55 and 85 years from Hyderabad, assessing their cognitive function and analyzing their blood samples for vitamins A, D, B1, B2, B6, B9, and B12, as well as certain neuronal biomarkers. The results showed that 36.4% of the participants were diagnosed with MCI. Those with MCI exhibited lower levels of vitamins D, B1, B2, B6, B9, and B12 in their blood. Notably, deficiencies in vitamins D, B2, and B9 were predominantly observed among those with MCI.
Additionally, the study found that participants with MCI had significantly higher blood sugar levels and systolic blood pressure compared to those without the condition. Interestingly, higher levels of vitamins D and B6 were associated with better cognitive performance. The researchers emphasized the importance of early nutritional assessment and timely intervention among older adults, highlighting the crucial role of maintaining adequate micronutrient status in supporting cognitive health and healthy aging.
However, the researchers also pointed out the need for further longitudinal studies and controlled trials to determine whether correcting vitamin deficiencies can prevent or reduce cognitive decline. Dr. Bharati Kulkarni, the director of the National Institute of Nutrition, stressed the significance of early nutritional assessment and early intervention in promoting cognitive well-being among the aging population.
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