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Circadian Oscillation Detection Analysis and Comparison (CODAC):a Multicriteria Method to Estimate and Compare Rhythmicity

Analysis of circadian patterns in time-series data requires computational methods that can accommodate several factors, including variable sampling resolution, replicate number, and missing values. Most existing tools simplify rhythmicity to a strict dichotomy based solely on a single p-value threshold. This leads to a level of uncertainty that affects many biological targets. We developed CODAC…

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