Structural rearrangements of PDGFRβ in the membrane upon activation by the viral oncoprotein E5
Proceedings of the National Academy of Sciences, Volume 123, Issue 34, August 2026. SignificanceThis work uncovers the molecular details by which the short viral oncoprotein, E5 from bovine papillomavirus, hijacks the platelet-derived growth factor receptor β (PDGFRβ) without any ligand. Using solid-state15N-NMR spectroscopy we ...
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