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Dissolution-Controlled Nanocrystalline Rifapentine Formulation for Tuberculosis Treatment

Current tuberculosis (TB) treatment suffers from drawbacks such as long regimens, high pill burden and side effects leading to non-adherence and poor treatment outcomes. Dissolution-controlled drug depot formulation with high drug loading is a clinically successful drug delivery strategy. Such depots reduce the dosing frequency for treatments requiring daily administration, thereby improving…

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Prevalence of non-spinal pathology and red flag diagnoses associated with care seeking for low back pain in the Military Health System

Scientific Reports, Published online: 17 August 2026; doi:10.1038/s41598-026-51658-w Prevalence of non-spinal pathology and red flag diagnoses associated with care seeking for low back pain in the…

  • 37.7% of low back pain patients were female
  • 2.9% of patients received red-flag diagnoses
  • Active-duty service members had higher vertebral fracture risk

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