A Bottom-Up Approach to Fungal Plasma Membrane Model: Lipid Mixture Design and Biophysical-Mechanical Characterization
The rising incidence of invasive fungal diseases emphasizes the need for novel therapeutic strategies, including membrane-targeting antifungal agents, which require representative lipid models for detailed molecular-level studies. In this work, we propose a consensus quinary fungal plasma membrane model based on lipidomic literature data, specifically PC:PE:PI:PA:PS phospholipid model with ratio…
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