Humanized mouse model could significantly improve preclinical research on drugs for celiac disease
Celiac disease is an autoimmune disorder in which the immune system reacts to gluten. More than 1% of the population in Germany is affected. In these individuals, gluten proteins found in wheat, rye and barley trigger inflammation in the small intestine, which can damage the intestinal villi and promote disease outside the intestinal tract. Despite following a gluten-free diet, up to 30% of…
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