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Monday, 10 August 2026 Reading Room

Science

Identifying multi-omics biomarkers for ovarian cancer survival estimation

Ovarian cancer is among the deadliest gynecologic malignancies, and its molecular heterogeneity limits accurate prognostic stratification. Although multi-omics approaches have improved predictive modeling, many prioritize predictive performance over biological interpretability, limiting their clinical translation. We developed an interpretable three-stage machine learning framework integrating…

biorxiv.org ·

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The heatwave is not just a temporary discomfort; it can have long-lasting effects on our bodies. Research has shown that a single episode of extreme heat can accelerate the biological aging process by as much as six months. This phenomenon is closely linked to climate change, which is causing temperatures to rise at an alarming rate. As the planet continues to warm up, the impact of heatwaves on human health is becoming increasingly evident. Heatwaves are not just a matter of discomfort; they can have serious consequences for our well-being. Prolonged exposure to high temperatures can lead to a range of health problems, from heat exhaustion to more severe conditions such as heatstroke. The biological clock, also known as the circadian rhythm, plays a crucial role in regulating our bodily functions. It is controlled by an intricate system that responds to light and darkness, and is influenced by external factors such as temperature and humidity. When we are exposed to extreme heat, our biological clock can get disrupted, leading to a range of physiological changes. Studies have shown that prolonged exposure to heat can lead to increased inflammation, oxidative stress, and DNA damage. These changes can accelerate the aging process, making us look and feel older than we actually are. In fact, research has shown that a single episode of extreme heat can increase biological age by as much as six months. The implications of this research are significant, particularly in the context of climate change. As temperatures continue to rise, we can expect to see more frequent and severe heatwaves. This means that we need to take urgent action to mitigate the effects of climate change and protect ourselves from the impacts of extreme heat. The Korean government has launched a series of initiatives to address the challenges posed by climate change. The Ministry of Environment has introduced a heatwave warning system, which provides early warnings to vulnerable populations such as the elderly and young children. The government has also launched a public awareness campaign to educate people on the risks associated with heatwaves and the steps they can take to protect themselves. In addition to these efforts, researchers are working to develop new technologies and strategies to mitigate the effects of heatwaves. For example, some scientists are exploring the use of cool roofs and green spaces to reduce urban heat islands. Others are developing new materials and systems that can help to keep buildings cool during extreme heat. As the world grapples with the challenges posed by climate change, it is clear that we need to take a proactive approach to protecting ourselves from the impacts of extreme heat. By working together, we can reduce the risks associated with heatwaves and create a more sustainable future for all.

·hani.co.kr

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