Researchers probe pesticide link to rising Parkinson’s disease cases

Nairobi, Kenya – Researchers are examining potential links between pesticides and the increasing prevalence of Parkinson's disease, according to a report from Capital FM. Dr. Richard Morton, a visiting scientist from Newcastle University, and Prof. Charles Newton of KEMRI-Wellcome Trust shared that certain pesticides, like paraquat and rotenone, are among the environmental factors most consistently associated with Parkinson's disease. Despite some pesticides being banned globally, their use persists in certain regions.

Scientists are also exploring other environmental exposures, such as trichloroethylene (TCE), an industrial cleaner, and air pollution from open fires, crop burning, and vehicle exhaust. Parkinson's disease, which occurs when cells in the brain stop producing dopamine, leads to a gradual worsening of movement control and currently has no cure, though medication, surgery, and therapy can manage symptoms.

The researchers emphasize that while environmental exposures may interact with genetic factors, the exact causes remain elusive. Some early symptoms, like loss of smell, constipation, and acting out dreams, may appear years before the characteristic movement problems. The World Health Organization reports that the number of people living with Parkinson's has doubled over the past three decades, with the highest risk among older individuals.

In Kenya, KEMRI-Wellcome Trust researchers are part of the Transforming Parkinson’s Care in Africa Research project, collecting soil, water, and biological samples to identify potential pesticide associations. They are also analyzing genetic data to better understand inherited factors. The research is timely, as Africa's aging population and improved health management are expected to increase neurological disease burdens.

However, the researchers highlight limited awareness and resources in Kenya, leading to challenges in diagnosis and treatment. They stress the need for policy action to improve Parkinson's management ahead of the projected rise in cases. While no conclusive evidence exists regarding diet or lifestyle changes to prevent Parkinson's, they stress the importance of exercise for those living with the condition.