New once-weekly HIV treatment shows promise in clinical trials
This is how a promising once-weekly HIV treatment could revolutionise medication adherence for patients, offering a simpler alternative to daily regimens.
A new once-weekly HIV treatment is showing promise in clinical trials, potentially allowing some people living with HIV to take their medication just once a week instead of every day. Researchers are increasingly focusing on long-acting HIV treatments that could reduce medication frequency while maintaining effective viral suppression.
In South Africa, daily antiretroviral medication remains a central part of the HIV treatment program. The new treatment combines islatravir and lenacapavir, designed to be taken once a week, and performed well in Phase 3 trials. However, it is not yet available to patients as it remains investigational. A weekly treatment could make medication management easier for some people, but adherence would still be crucial.
The once-weekly pill is part of a trend towards HIV medicines not requiring daily intake. Long-acting HIV medicines are already available in various intervals, and the WHO supports long-acting injectable cabotegravir and rilpivirine for some patients. South Africa is also introducing long-acting lenacapavir for HIV prevention. While a weekly pill could offer convenience, it's important that people living with HIV continue taking their current medication as prescribed and consult their healthcare provider before making any changes.
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