Scientists unmask immune cells that supercharge the fight against cancer
A little-known group of hard-to-find immune cells could help transform cancer treatment, scientists at the University of Manchester's Cancer Research UK Manchester Institute have found. Their discovery, accepted for publication in the journal Immunity, centers on activated dendritic cells, a specialized population of immune cells that orchestrate the body's attack on cancer. It is available on…
Scientists at the University of Manchester's Cancer Research UK Manchester Institute have identified a group of immune cells that amplify the body's defense against cancer, according to a new study. Published in the journal Immunity, the research highlights the crucial role of activated dendritic cells in cancer immunotherapy. These specialized immune cells are responsible for coordinating the body's attack on cancer cells and are essential for both spontaneous immune control of cancer and the effectiveness of immunotherapy treatments.
Researchers developed innovative mouse models to study these cells, which revealed that their absence impairs the immune system's ability to control cancer and respond to immunotherapy. The findings could potentially lead to new strategies to enhance the efficacy of cancer treatments and benefit more patients.
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