Traditional Japanese medicine may ease age-related fat tissue scarring
A traditional Japanese medicine used for obesity may do more than support weight loss. Researchers at the University of Osaka, working with Kobayashi Pharmaceutical Co., Ltd., investigated whether Bofutsushosan could protect aging tissues from fibrosis—the excessive buildup of scar-like tissue that can make organs stiff and less functional. The study was published in the journal Phytomedicine.
A traditional Japanese medicine, Bofutsushosan, used for obesity treatment, may also help ease age-related fat tissue scarring, according to a study by researchers at the University of Osaka. The study, published in the journal Phytomedicine, investigated whether Bofutsushosan could protect aging tissues from fibrosis, the excessive buildup of scar-like tissue that can make organs stiff and less functional.
The researchers found that mice fed a high-fat diet with 2% Bofutsushosan weighed less, had smaller fat deposits, showed less fat buildup in the liver, and had fewer fibrosis-related changes in fat tissue and the liver compared to untreated mice. The effects were attributed to several ingredients in Bofutsushosan, with Forsythiae Fructus, Zingiberis Rhizoma, Rhei Rhizoma, and Scutellariae Radix showing particularly strong antifibrotic activity in cultured cells.
Further research is needed to determine if these findings can contribute to treatments for fibrosis associated with obesity and aging.
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