Highlights from the first-ever Neural Genetics and Epigenetics Gordon Research Conference
The meeting’s organizers recap the science to watch.
The first-ever Neural Genetics and Epigenetics Gordon Research Conference took place at Colby-Sawyer College in rural New Hampshire last week. Around 120 genetic neuroscientists from around the world gathered to present their work on various aspects of neuronal epigenetic regulation over a span of five days. Organizers and attendees discussed major themes, takeaways, and standout talks from the conference.
One of the noteworthy themes at the conference was the shift from focusing on individual genes or marks to understanding epigenetic regulation at an integrated level. Researchers emphasized the importance of considering gene programs as whole systems and how manipulating certain chromatin marks can impact other compartments within the nucleus. For example, disrupting heterochromatin can affect the organization of euchromatin, two primary compartments within the nucleus.
The conference also highlighted progress in understanding the role of epigenetic mechanisms in neuroplasticity and brain development. Angel Barco from Instituto de Neurociencias de Alicante noted that the field has expanded and matured, with researchers now utilizing a broader range of approaches beyond the latest emerging technologies.
Maria Chahrour from University of Texas Southwestern Medical Center pointed out the value in studying individual genes in depth, as it enables a better understanding of the mechanisms at play and their collective impact on broader themes.
Some standout talks included Ian Maze's presentation, which brought a biochemical perspective to the study of the nucleus, and Shelley Berger's research on how epigenetic changes regulate ant behavior and social roles. Zhaolan (Joe) Zhou from the University of Pennsylvania appreciated talks that explored epigenetics from an evolutionary perspective, particularly those by Ava Carter and Debbie Silver from Michael Greenberg's lab.
These talks aimed to understand how epigenetic mechanisms have evolved across species, aiding in the translation of discoveries from model systems to humans.
Written by urgent.news from The Transmitter's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.
