Is George Pickens playing today? Latest injury update for Cowboys WR in Week 10

In the recent Cowboys game against the Indianapolis Colts, wide receiver CeeDee Lamb received the majority of passing targets, totaling 16 in Week 9. This marked the third-most targets he has accumulated so far this season, as he secured 10 catches for 195 yards and a touchdown. However, the increased volume came without the participation of George Pickens, who missed the game due to injury.

Pickens' snap count had declined over the last two weeks, with him missing 19 of 28 second-half snaps in Week 7 and playing only 42 of 74 offensive snaps against the Cardinals in Week 8. After sitting out Week 9, it remains uncertain whether Pickens will play in Sunday's matchup against the San Francisco 49ers.

Pickens did practice this week, but his availability remained in question due to limited participation in Wednesday and Thursday sessions. On Friday, however, he was deemed a full participant, suggesting that his hamstring issues have been resolved. Pickens confidently stated to the media, "Tell your wife or your girl to turn the TV on, and she'll see me on the field," indicating his intent to play in the upcoming game. The Cowboys face the San Francisco 49ers on Sunday, November 15, 2026, at 3:25 pm CT on FOX.