Unsupervised Deep Learning for Cryo-EM/ET Particle Classification
Cryogenic electron microscopy (cryo-EM) is widely used to determine protein structures from purified samples. With cryogenic electron tomography (cryo-ET), it is possible to image thin sections of cells and directly visualize diverse proteins in their native environment. However, separating the massive mixture of different types of proteins inside cells remains challenging, especially without…
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